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Co-activation of - and -opioid receptors elicits tolerance to morphine-induced ventilatory depression via generation of peroxynitrite

115, E1560E1569

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This proposes that the coexistence of helminths and their human hosts over millennia has enabled them to potently regulate the mammalian immune system and skew responses to be anti-inflammatory/tolerogenic/reparative (7981)

In response to neuroinflammation, macrophages could be activated into anti-inflammatory state, serving as protectors digesting cell debris and pathogens, as well as releasing anti-inflammatory factors and activating other immune cells